Anti-B3GALNT1 aptamer SELEX Service(Cat#: CTApt-1659)

This is an aptamer development services to screening aptamers binds to the B3GALNT1 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target B3GALNT1
Alternative Names Beta-1,3-N-Acetylgalactosaminyltransferase 1 (Globoside Blood Group) ; Globoside Synthase; Beta3Gal-T3; UDP-N-Acetylgalactosamine:Globotriaosylceramide Beta-1,3-N-Acetylgalactosaminyltransferase; UDP-Gal:BetaGlcNAc Beta 1,3-Galactosyltransferase, Polypeptide 3 (Globoside Blood Group) ; Galactosylgalactosylglucosylceramide Beta-D-Acetyl-Galactosaminyltransferase; UDP-GalNAc:Beta-1,3-N-Acetylgalactosaminyltransferase 1; Beta-1,3-Galactosyltransferase 3; P Antigen Synthase; Beta-1,3-GalNAc-T1; Beta-1,3-GalTase 3; Beta-3-Gx-T3; EC 2.4.1.79; B3Gal-T3; B3GALT3 ; GalT3; GLOB; P1; UDP-GalNAc:BetaGlcNAc Beta 1,3-Galactosaminyltransferase, Polypeptide 1 (Globoside Blood Group) ; UDP-GalNAc:BetaGlcNAc Beta-1,3-Galactosaminyltransferase, Polypeptide 1 (Globoside Blood Group) ; Globotriaosylceramide 3-Beta-N-Acetylgalactosaminyltransferase; P Blood Group Globoside; Beta3GalT3; Brainiac1; B3GALNT1; Gb4Cer; GLCT3
Gene ID 8706
UniProt ID O75752
Target Overview This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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