Anti-B4GALT4 aptamer SELEX Service(Cat#: CTApt-1852)
This is an aptamer development services to screening aptamers binds to the B4GALT4 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
B4GALT4 |
| Alternative Names |
Beta-1,4-Galactosyltransferase 4; Beta4Gal-T4; UDP-Galactose:Beta-N-Acetylglucosamine Beta-1,4-Galactosyltransferase 4; UDP-Gal:BetaGlcNAc Beta 1,4- Galactosyltransferase, Polypeptide 4; UDP-Gal:Beta-GlcNAc Beta-1,4-Galactosyltransferase 4; Lactotriaosylceramide Beta-1,4-Galactosyltransferase; N-Acetyllactosamine Synthase; Beta-1,4-GalTase 4; Nal Synthase; B4Gal-T4; Beta-N-Acetylglucosaminyl-Glycolipid Beta-1,4-Galactosyltransferase 4; Beta-N-Acetylglucosaminyl-Glycolipid Beta-1,4-Galactosyltransferase; UDP-Gal:BetaGlcNAc Beta 1,4- Galactosyltransferase 4; EC 2.4.1.275; EC 2.4.1.90; B4GALT4 |
| Gene ID |
8702 |
| UniProt ID |
O60513 |
| Target Overview |
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcript variants have been found for this gene. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
