Anti-BCAT1 aptamer SELEX Service(Cat#: CTApt-1708)
This is an aptamer development services to screening aptamers binds to the BCAT1 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
BCAT1 |
| Alternative Names |
Branched Chain Amino Acid Transaminase 1; Branched-Chain-Amino-Acid Aminotransferase, Cytosolic; Branched Chain Aminotransferase 1, Cytosolic; EC 2.6.1.42; ECA39; BCT1; Branched Chain Amino-Acid Transaminase 1, Cytosolic; Placental Protein 18; Protein ECA39; PNAS121; BCAT(C) ; MECA39; BCATC; BCAT1; BCATc; PP18 |
| Gene ID |
586 |
| UniProt ID |
P54687 |
| Target Overview |
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
