Anti-BCDIN3D aptamer SELEX Service(Cat#: CTApt-1711)
This is an aptamer development services to screening aptamers binds to the BCDIN3D with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
BCDIN3D |
| Alternative Names |
BCDIN3 Domain Containing RNA Methyltransferase; RNA 5'-Monophosphate Methyltransferase; BCDIN3 Domain-Containing Protein; BCDIN3 Domain Containing RNA Methyltransfease; Pre-MiRNA 5'-Monophosphate Methyltransferase; Probable Methyltransferase BCDIN3D; BCDIN3 Domain Containing; EC 2.1.1; BCDIN3D |
| Gene ID |
144233 |
| UniProt ID |
Q7Z5W3 |
| Target Overview |
This gene encodes an RNA methyltransferase which belongs to the rossmann fold methyltransferase family, and serves as a 5'-methylphosphate capping enzyme that is specific for cytoplasmic histidyl tRNA. The encoded protein contains an S-adenosylmethionine binding domain and uses the methyl group donor, S-adenosylmethionine. This gene is overexpressed in breast cancer cells, and is related to the tumorigenic phenotype and poor prognosis of breast cancer. The encoded protein is thought to promote the cellular invasion of breast cancer cells, by downregulating the expression of tumor suppressor miRNAs through the dimethylation of the 5-monophosphate of the corresponding precursor miRNAs. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
