Anti-BCL2L2 aptamer SELEX Service(Cat#: CTApt-1722)
This is an aptamer development services to screening aptamers binds to the BCL2L2 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
BCL2L2 |
| Alternative Names |
BCL2 Like 2; Protein Phosphatase 1, Regulatory Subunit 51; Bcl-2-Like Protein 2; KIAA0271; PPP1R51; BCL-W; BCL; Apoptosis Regulator BCL-W; Apoptosis Regulator Bcl-W; BCL2-L-; Bcl2-L-2; BCL2L2 |
| Gene ID |
599 |
| UniProt ID |
Q92843 |
| Target Overview |
This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
