This is an aptamer development services to screening aptamers binds to the BECN1 with an affinity of 1nM~1μM.
Target Category | Protein |
Target | BECN1 |
Alternative Names | Beclin 1; Coiled-Coil Myosin-Like BCL2-Interacting Protein; Beclin 1, Autophagy Related; Beclin-1; VPS30; ATG6; Beclin 1 (Coiled-Coil, Moesin-Like BCL2 Interacting Protein ; Beclin 1 (Coiled-Coil, Moesin-Like BCL2-Interacting Protein) ; ATG6 Autophagy Related 6 Homolog (S. Cerevisiae) ; Testis Secretory Sperm-Binding Protein Li 215e; ATG6 Autophagy Related 6 Homolog; Protein GT197; Beclin1; BECN1; GT197 |
Gene ID | 8678 |
UniProt ID | Q14457 |
Target Overview | This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. |
Chemical Modification | N/A |
Type | DNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |