This product is an aptamer which binds to BFT-2 with a high affinity.
Target Category | Protein |
Target | BFT-2 |
Alternative Names | Bacteroides fragilis toxin |
Target Overview | BFT-2 is a isotypes of Bacteroides fragilis toxin (BFT) which is a zinc-dependent metalloprotease toxin secreted by Enterotoxigenic Bacteroides fragilis (ETBF) and can bind to an uncharacterized receptor on the surface of epithelial resulting in junctional cleavage causing chronic colitis. ETBF has also associated in colorectal cancer and irritable bowel disease patients. |
Type | DNA |
Species Reactivity | Bacteria |
Length | 50-200 nt |
Binding Conditions/Buffer | 10 mM Tris-HCl, 1mM EDTA, and 2 M NaCl, pH 7.5 |
GC Content | 41.18% |
Molecular Weight | 20451.4 g/mole |
nmoles/OD260 | 1.317 |