Anti-BMP8B aptamer SELEX Service(Cat#: CTApt-1924)
This is an aptamer development services to screening aptamers binds to the BMP8B with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
BMP8B |
| Alternative Names |
Bone Morphogenetic Protein 8b; Osteogenic Protein 2; Bone Morphogenetic Protein 8 (Osteogenic Protein 2) ; Bone Morphogenetic Protein 8B; BMP8; OP-2; BMP-8B; BMP8B; BMP-8; OP2 |
| Gene ID |
656 |
| UniProt ID |
P34820 |
| Target Overview |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
