Anti-BMPR1A aptamer SELEX Service(Cat#: CTApt-1768)
This is an aptamer development services to screening aptamers binds to the BMPR1A with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
BMPR1A |
| Alternative Names |
Bone Morphogenetic Protein Receptor Type 1A; ALK3; Bone Morphogenetic Protein Receptor, Type IA; Bone Morphogenetic Protein Receptor Type-1A; Serine/Threonine-Protein Kinase Receptor R5; Activin Receptor-Like Kinase 3; BMP Type-1A Receptor; EC 2.7.11.30; ACVRLK3; BMPR-1A; CD292; ALK-3; SKR5; Activin A Receptor, Type II-Like Kinase 3; CD292 Antigen; EC 2.7.1; 10q23del; BMPR1A |
| Gene ID |
657 |
| UniProt ID |
P36894 |
| Target Overview |
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
