This product is an aptamer which binds to the Cancer stem cell marker epithelial cell adhesion molecule with an affinity of <50 nM.
Target Category | Protein |
Target | Cancer stem cell marker epithelial cell adhesion molecule |
Chemical Modification | 2'-F-RNA |
Length | 20-40 nt |
Affinity (Kd) | <50 nM |
Binding Conditions/Buffer | Assay Buffer: DPBS with 5 mM MgCl2, 0.1 mg/ml tRNA, 0.1 mg/ml salmon sperm DNA, 02% [w/v] sodium azide, and 5% FCS. The final concentration of MgCl2 was 2.5 mM. |
GC Content | 0.6842 |
Molecular Weight | 6392.85 g/mole |
Extinction Coefficient | 188200 L/(mole·cm) |
nmoles/OD260 | 5.31 |
Revolutionize our EpCAM-related studiesExcellentIts ability to discriminate between different EpCAM expression levels allowed us to dissect complex biological processes. The aptamer's cost-effectiveness and user-friendly documentation make it a top choice.
The anti-EpCAM aptamer exceeded my expectationsExcellentIts binding affinity and stability were exceptional, enabling us to design innovative experiments. The aptamer's compatibility with different buffers and conditions made it a breeze to integrate into our existing protocols.
High specificity and sensitivityExcellentThe easy-to-follow protocol and consistent results make this aptamer a must-have for any molecular biologist.