Anti-GDF11 Aptamer SELEX Service(Cat#: CTApt-762)

This is an aptamer development services to screening aptamers binds to the GDF11 with an affinity of 1nM~1μM.

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5’ Modification
 
3’ Modification
 
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Summary

Specifications
Target Category Protein
Target GDF11
Alternative Names BMP11; BMP-11
Gene ID 10220
UniProt ID O95390
Target Overview This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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