This is an aptamer development services to screening aptamers binds to the GDF11 with an affinity of 1nM~1μM.
Target Category | Protein |
Target | GDF11 |
Alternative Names | BMP11; BMP-11 |
Gene ID | 10220 |
UniProt ID | O95390 |
Target Overview | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. |
Chemical Modification | N/A |
Type | DNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |