Anti-Human C5aR1 Aptamer(Cat#: CTMM-0124-RJ18)
This product is an aptamer which binds to Human C5aR1 with an affinity of <50 pM.
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Summary
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Specifications
| Target Category |
Protein |
| Target |
C5aR1 |
| Alternative Names |
Complement C5a Receptor 1; C5AR; CD88; C5R1; C5A; C5a Anaphylatoxin Chemotactic Receptor; Complement Component 5a Receptor 1; C5a-R; Complement Component 5 Receptor 1 (C5a Ligand); C5a Anaphylatoxin Chemotactic Receptor; C5a Anaphylatoxin Receptor; CD88 Antigen; C5a Ligand; C5aR; C5aR1 |
| Gene ID |
728 |
| UniProt ID |
P21730 |
| Target Overview |
Enables G protein-coupled receptor activity and complement component C5a receptor activity. Involved in several processes, including complement component C5a signaling pathway; mRNA transcription by RNA polymerase II; and positive regulation of ERK1 and ERK2 cascade. Located in apical part of cell and basolateral plasma membrane. Biomarker of Alzheimer's disease; asthma; chronic obstructive pulmonary disease; rhinitis; and severe acute respiratory syndrome. |
| Type |
RNA |
| Species Reactivity |
Human |
| Length |
100-200 nt |
| Affinity (Kd) |
<50 pM |
| Binding Conditions/Buffer |
10 mM HEPES, 150 mM NaCl, pH 7.4 |
| GC Content |
58.41% |
| Molecular Weight |
34292.7 g/mole |
| nmoles/OD260 |
0.807 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
