This product is an aptamer which binds to Human CD109 domain with an affinity of 1-50 nM.
Target Category | Protein |
Target | CD109 |
Alternative Names | CD109 Molecule; CPAMD7; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 7; 150 KDa TGF-Beta-1-Binding Protein; Platelet-Specific Gov Antigen; DKFZp762L1111; CD109 Antigen; FLJ38569; P180; R150; CD109 Antigen (Gov Platelet Alloantigens); Activated T-Cell Marker CD109; Gov Platelet Alloantigens |
Gene ID | 135228 |
UniProt ID | Q6YHK3 |
Target Overview | This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene. |
Type | DNA |
Species Reactivity | Human |
Length | 50-100 nt |
Affinity (Kd) | 1-50 nM |
Binding Conditions/Buffer | Dulbecco's phosphate buffered saline (D-PBS, Ca2+/Mg2+-free) with 4.5 g/L of glucose and 5 mM of MgCl2 added with 0.1 mg/mL of yeast tRNA, and 1 mg/mL of BSA |
GC Content | 51.22% |
Molecular Weight | 25406.3 g/mole |
nmoles/OD260 | 1.122 |