Anti-Human CD109 Aptamer(Cat#: CTMM-0124-LH10)

This product is an aptamer which binds to Human CD109 domain with an affinity of 1-50 nM.

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5’ Modification
 
3’ Modification
 
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Summary

Specifications
Target Category Protein
Target CD109
Alternative Names CD109 Molecule; CPAMD7; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 7; 150 KDa TGF-Beta-1-Binding Protein; Platelet-Specific Gov Antigen; DKFZp762L1111; CD109 Antigen; FLJ38569; P180; R150; CD109 Antigen (Gov Platelet Alloantigens); Activated T-Cell Marker CD109; Gov Platelet Alloantigens
Gene ID 135228
UniProt ID Q6YHK3
Target Overview This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene.
Type DNA
Species Reactivity Human
Length 50-100 nt
Affinity (Kd) 1-50 nM
Binding Conditions/Buffer Dulbecco's phosphate buffered saline (D-PBS, Ca2+/Mg2+-free) with 4.5 g/L of glucose and 5 mM of MgCl2 added with 0.1 mg/mL of yeast tRNA, and 1 mg/mL of BSA
GC Content 51.22%
Molecular Weight 25406.3 g/mole
nmoles/OD260 1.122
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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