This product is an aptamer which binds to the Human ETS1 with an affinity of high affinity.
Target Category | Protein |
Target | ETS1 |
Alternative Names | ETS Proto-Oncogene 1, Transcription Factorc; ETS-1; EWSR2; Avian Erythroblastosis Virus E26 (V-Ets) Oncogene Homolog-1; V-Ets Avian Erythroblastosis Virus E26 Oncogene Homolog 1; Protein C-Ets-1; P54; V-Ets Avian Erythroblastosis Virus E2 Oncogene Homolog 1; Ets Protein; C-Ets-1 |
Gene ID | 2113 |
UniProt ID | P14921 |
Target Overview | This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Chemical Modification | 2'-O-Methyl pyrimidines |
Type | RNA |
Species Reactivity | Human |
Length | 50-100 nt |
Binding Conditions/Buffer | EBSS with 1 mM MgCl₂ |
GC Content | 50.57% |
Molecular Weight | 26451.64 g/mole |
nmoles/OD260 | 1.26 |