Anti-Human ETS1 Aptamer(Cat#: CTMM-0124-TT31)

This product is an aptamer which binds to the Human ETS1 with an affinity of high affinity.

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5’ Modification
 
3’ Modification
 
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Summary

Specifications
Target Category Protein
Target ETS1
Alternative Names ETS Proto-Oncogene 1, Transcription Factorc; ETS-1; EWSR2; Avian Erythroblastosis Virus E26 (V-Ets) Oncogene Homolog-1; V-Ets Avian Erythroblastosis Virus E26 Oncogene Homolog 1; Protein C-Ets-1; P54; V-Ets Avian Erythroblastosis Virus E2 Oncogene Homolog 1; Ets Protein; C-Ets-1
Gene ID 2113
UniProt ID P14921
Target Overview This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Chemical Modification 2'-O-Methyl pyrimidines
Type RNA
Species Reactivity Human
Length 50-100 nt
Binding Conditions/Buffer EBSS with 1 mM MgCl₂
GC Content 50.57%
Molecular Weight 26451.64 g/mole
nmoles/OD260 1.26
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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