Anti-Human FLT1 Aptamer(Cat#: CTApt-835)
This product is an aptamer which binds to the Human FLT1 with an affinity of 1-50 nM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
FLT1 |
| Alternative Names |
Fms Related Receptor Tyrosine Kinase 1; VEGFR1; Vascular Endothelial Growth Factor Receptor 1; Vascular Permeability Factor Receptor; FLT; Fms-Related Tyrosine Kinase 1 (Vascular Endothelial Growth Factor/Vascular Permeability Factor Receptor); Tyrosine-Protein Kinase Receptor FLT; Fms Related Tyrosine Kinase 1; Tyrosine-Protein Kinase FRT; Fms-Like Tyrosine Kinase 1; VEGFR-1; FLT-1; Fms-Related Tyrosine Kinase 1; FRT |
| Gene ID |
2321 |
| UniProt ID |
P17948 |
| Target Overview |
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia. |
| Type |
DNA |
| Species Reactivity |
Human |
| Length |
<50 nt |
| Affinity (Kd) |
1-50 nM |
| Binding Conditions/Buffer |
PBS with 2 mM EDTA and 0.1% w/w Human albumin |
| GC Content |
44.12% |
| Molecular Weight |
10424.82 g/mole |
| nmoles/OD260 |
3.36 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
