Anti-Human Matrix Metalloproteinase 9 (MMP9) Aptamer(Cat#: CTMM-0124-JS5)

This product is an aptamer that binds to the Human Matrix Metalloproteinase 9 (MMP9) protein with an affinity of <50 nM.

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Specifications
Target Category Protein
Target MMP9
Alternative Names Matrix Metallopeptidase 9; CLG4B; Matrix Metalloproteinase 9 (Gelatinase B; 92kDa Gelatinase; 92kDa Type IV Collagenase); Matrix Metalloproteinase-9; EC 3.4.24.35; MMP-9; GELB; Matrix Metallopeptidase 9 (Gelatinase B; 92kDa Gelatinase; 92kDa Type IV Collagenase); 92 KDa Type IV Collagenase; Macrophage Gelatinase; Type V Collagenase; 92 KDa Gelatinase; Gelatinase B; EC 3.4.24; MANDP2
Gene ID 4318
UniProt ID P14780
Target Overview Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and Mouse studies suggest a role in tumor-associated tissue remodeling.
Type DNA
Species Reactivity Human
Length 50-200 nt
Affinity (Kd) <50 nM
Binding Conditions/Buffer 20 mM MOPS, 150mM NaCl, 1 mM CaCl₂
GC Content 43.90%
Molecular Weight 12149.95 g/mole
nmoles/OD260 2.97
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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