This is an aptamer development services to screening aptamers binds to the KRT19 with an affinity of 1nM~1μM.
Target Category | Protein |
Target | KRT19 |
Alternative Names | Keratin 19; Keratin, Type I Cytoskeletal 19; K19; 40-KDa Keratin Intermediate Filament; Keratin, Type I, 40-Kd; Keratin 19, Type I; Cytokeratin 19; CK-19; CK19; K1CS; Cytokeratin-19; Keratin-19; MGC15366; KRT19 |
Gene ID | 3880 |
UniProt ID | P08727 |
Target Overview | The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. |
Chemical Modification | N/A |
Type | DNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |