Anti N-glycolylneuraminic acid (Neu5Gc) Aptamer(Cat#: CTApt-2574)
This product is an aptamer which binds to the N-glycolylneuraminic acid (Neu5Gc) with an affinity of <20 nM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Small Organic |
| Target |
N-glycolylneuraminic acid (Neu5Gc) |
| Target Overview |
N-Glycolylneuraminic acid (Neu5Gc) is a sialic acid molecule found in most non-human mammals. Humans cannot synthesize Neu5Gc because the human gene CMAH is irreversibly mutated, though it is found in other apes. It is absent in human tissues because of inactivation of gene encoding CMP-N-acetylneuraminic acid hydroxylase. |
| Chemical Modification |
DNA |
| Length |
80-100 nt |
| Affinity (Kd) |
<20 nM |
| Binding Conditions/Buffer |
Sodium carbonate buffer, pH 9.6 |
| GC Content |
0.59 |
| Molecular Weight |
24917.1 |
| nmoles/OD260 |
1.235 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
