This product is an aptamer which binds to the NAD with an affinity of <20 nM.
Target Category | Small Organic |
Target | NAD |
Alternative Names | Nicotinamide adenine dinucleotide |
Target Overview | Nicotinamide adenine dinucleotide (NAD) is a coenzyme central to metabolism. Found in all living cells, NAD is called a dinucleotide because it consists of two nucleotides joined through their phosphate groups. One nucleotide contains an adenine nucleobase and the other nicotinamide. |
Chemical Modification | RNA |
Length | 40-60 nt |
Affinity (Kd) | <20 nM |
Binding Conditions/Buffer | 20 mM HEPES (pH 7.5), 300 mM KC1, and 5 mM MgC12) at room temperature. |
GC Content | 0.5918 |
Molecular Weight | 15748.56 g/mole |
Extinction Coefficient | 474700 L/(mole·cm) |
nmoles/OD260 | 2.11 |