This product is an aptamer which binds to the Rituximab with an affinity of <400 nM.
Target Category | Antibody |
Target | Rituximab |
Alternative Names | N/A |
Gene ID | N/A |
UniProt ID | N/A |
Target Overview | Rituximab, one of the most important biologics in cancer treatment, is a chimeric monoclonal anti-CD20 antibody produced in Chinese hamster ovary (CHO) cells. |
Chemical Modification | DNA |
Length | 20-40 nt |
Affinity (Kd) | <400 nM |
Binding Conditions/Buffer | 20 mM Tris-HCl pH 7.6, 100 mM NaCl, 2 mM MgCl₂, 5 mM KCl, 1 mM CaCl₂, 0.02% v/v Tween 20 |
GC Content | 55 |
Molecular Weight | 12350.1 |
Extinction Coefficient | 371900 |
nmoles/OD260 | 2.43 |