Anti-SPP1 Aptamer(Cat#: CTApt-808)
This product is an aptamer which binds to the SPP1 with an affinity of 1-50 nM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
SPP1 |
| Alternative Names |
Secreted Phosphoprotein; Osteopontin; Early T-Lymphocyte Activation; Urinary Stone Protein; Nephropontin; Uropontin; ETA-1; BNSP; BSPI; OPN; Secreted Phosphoprotein 1 (Osteopontin, Bone Sialoprotein I, Early T-Lymphocyte Activation 1); Osteopontin/Immunoglobulin Alpha 1 Heavy Chain Constant Region Fusion Protein 3; Secreted Phosphoprotein 1 Variant 6; Bone Sialoprotein I; SPP1/CALPHA1 Fusion; Bone Sialoprotein; SPP-1; SPP1 |
| Gene ID |
6696 |
| UniProt ID |
P10451 |
| Target Overview |
The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. |
| Chemical Modification |
RNA |
| Length |
<50 nt |
| Affinity (Kd) |
1-50 nM |
| Binding Conditions/Buffer |
137 nmol/L NaCl, 27 nmol/L KCl, 100 nmol/L Na2HPO4, 2 nmol/L K2HPO4 , pH 7.4 |
| GC Content |
45% |
| Molecular Weight |
12186.8 |
| nmoles/OD260 |
2.187 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
