This product is an aptamer which binds to the Toll-like receptor 3 Ectodomain with an affinity of <20 nM.
Target Category | Protein |
Target | Toll-like receptor 3 Ectodomain |
Chemical Modification | RNA |
Length | 60-80 nt |
Affinity (Kd) | <20 nM |
Binding Conditions/Buffer | Binding buffer: 2 mM HEPES-NaOH (pH 7.6), 3 mM MgCl2, and 100 mM NaCl |
GC Content | 0.6094 |
Molecular Weight | 20703.58 g/mole |
Extinction Coefficient | 628900 L/(mole·cm) |
nmoles/OD260 | 1.59 |
Obtained reproducible results in my experimentsExcellentThe aptamer binds to the target with high affinity and specificity, allowing us to study the receptor's activation and downstream effects. I am very pleased with this aptamer's performance.
It has allowed us to study the receptor's involvement in immune dysregulationExcellentI purchased the anti-TLR3-ECD aptamer for my research on autoimmune diseases, and it has been phenomenal. The aptamer's binding affinity to TLR3 is remarkable.
For studying TLR3-related signaling pathwaysExcellentThis aptamer has greatly contributed to our research progress, and I would highly recommend it to others.