This product is an aptamer which binds to the Verotoxin with an affinity of 1-50 μM.
Target Category | Protein |
Target | Verotoxin |
Alternative Names | Shiga toxins |
Target Overview | Shiga toxins are a family of related toxins with two major groups, Stx1 and Stx2, expressed by genes considered to be part of the genome of lambdoid prophages. The toxins are named after Kiyoshi Shiga, who first described the bacterial origin of dysentery caused by Shigella dysenteriae. Shiga-like toxin (SLT) is a historical term for similar or identical toxins produced by Escherichia coli. The most common sources for Shiga toxin are the bacteria S. dysenteriae and some serotypes of Escherichia coli (STEC), which includes serotypes O157:H7, and O104:H4. |
Type | Peptide |
Species Reactivity | Bacteria |
Length | <50 aa |
Affinity (Kd) | 1-50 μM |
Binding Conditions/Buffer | 50 mM Tris/acetate, 150 mM NaCl, 50 mM magnesium acetate and 0.05 % Tween 20, pH 7 |