C-Reactive Protein

Clear All
Specie Reactivity Human
Sensitivity 0.156 ng/mL (0.625-40 ng/mL)
Applications ELISA
Specie Reactivity Human
Sensitivity 0.129 ng/mL (0.312-20 ng/mL)
Applications ELISA
Specie Reactivity Human
Sensitivity 5 ng/mL (5-4000 ng/mL)
Applications ELISA
Specie Reactivity Human
Sensitivity 3.9 ng/mL (15.6-1000 ng/mL)
Applications ELISA
Specie Reactivity Human
Sensitivity 0.062 ng/mL (0.156-10 ng/mL)
Applications ELISA
Specie Reactivity Rat
Sensitivity 0.30 ng/mL (0.78-50 ng/mL)
Applications ELISA
Specie Reactivity Rat
Sensitivity 7.81 ng/mL (31.25-2000 ng/mL)
Applications ELISA
Specie Reactivity Rat
Sensitivity 0.05 ng/mL (0.14-100 ng/mL)
Applications ELISA
Specie Reactivity Rabbit
Sensitivity 0.28 ng/mL (0.78-50 ng/mL)
Applications ELISA
Specie Reactivity Rabbit
Sensitivity 2 pg/mL (7.8-2000 pg/mL)
Applications ELISA
Specie Reactivity Chicken
Sensitivity 0.211 ng/mL (0.625-40 ng/mL)
Applications ELISA
Specie Reactivity Chicken
Sensitivity 27.7 pg/mL (62.5-4000 pg/mL)
Applications ELISA
Specie Reactivity Porcine
Sensitivity 46.875 pg/mL (78.125-5000 pg/mL)
Applications ELISA
Specie Reactivity Porcine
Sensitivity 0.156 ng/mL (0.625-40 ng/mL)
Applications ELISA
Specie Reactivity Porcine
Sensitivity 0.31 ng/mL (0.78-50 ng/mL)
Applications ELISA
Specie Reactivity Guinea Porcine
Sensitivity 0.375 ng/mL (0.625-40 ng/mL)
Applications ELISA
Specie Reactivity Guinea Porcine
Sensitivity 6.4 pg/mL (15.6-1000 pg/mL)
Applications ELISA
Specie Reactivity Bovine
Sensitivity 5.6 pg/mL (15.6-1000 pg/mL)
Applications ELISA
Specie Reactivity Bovine
Sensitivity 1.25 ng/mL (1.25-80 ng/mL)
Applications ELISA
Specie Reactivity Ovine
Sensitivity 0.156 μg/mL (0.625-40 μg/mL)
Applications ELISA
Specie Reactivity Ovine
Sensitivity 35 pg/mL (78-5000 pg/mL)
Applications ELISA
Specie Reactivity Monkey
Sensitivity 18.75 pg/mL (31.25-2000 pg/mL)
Applications ELISA
Specie Reactivity Monkey
Sensitivity 0.156 ng/mL (0.625-40 ng/mL)
Applications ELISA
Specie Reactivity Canine
Sensitivity 0.064 ng/mL (0.15-10 ng/mL)
Applications ELISA
Specie Reactivity Canine
Sensitivity 0.078 μg/mL (0.312-20 μg/mL)
Applications ELISA
Specie Reactivity Equine
Sensitivity 0.039 ng/mL (0.156-10 ng/mL)
Applications ELISA
Specie Reactivity Hamster
Sensitivity 3.12 ng/mL (12.5-800 ng/mL)
Applications ELISA
Clear All
Host Animal Mouse
Specie Reactivity Human; Mouse; Rat; Pocine
Antibody Clone CTJS-52
Isotype IgG2a
Applications WB
Host Animal Mouse
Specie Reactivity Human
Antibody Clone CTJS-246
Isotype IgG1
Applications WB; ELISA; FC; IHC
Host Animal Mouse
Specie Reactivity Human
Antibody Clone CTJS-607
Isotype IgG2b
Applications ELISA
Host Animal Mouse
Specie Reactivity Human
Antibody Clone CTJS-590
Isotype IgG2a
Applications WB
Host Animal Mouse
Specie Reactivity Human
Antibody Clone CTJS-749
Isotype IgG2a κ
Applications WB; ELISA; FC; IF
Host Animal Mouse
Specie Reactivity Rat
Antibody Clone CTJS-633
Isotype IgG2a
Applications ELISA
Host Animal Rat
Specie Reactivity Mouse
Antibody Clone CTJS-386
Isotype IgG2a
Applications ELISA
Host Animal Goat
Specie Reactivity Human
Isotype IgG
Applications ELISA; Immunodiffusion
Host Animal Sheep
Specie Reactivity Human
Isotype IgG
Applications WB; IHC; IF
Host Animal Goat
Specie Reactivity Mouse
Isotype IgG
Applications WB; IHC
Host Animal Goat
Specie Reactivity Rat
Isotype IgG
Applications WB; IHC
Host Animal Mouse
Specie Reactivity Rat
Antibody Clone TJL-233
Isotype IgG2b
Applications WB
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-234
Isotype IgG2b
Applications ELISA
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-236
Isotype IgG2a Kappa
Applications WB; ELISA; Flow; ICC/IF
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-238
Isotype IgG1
Applications WB; ELISA; IA; IHC; AP
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-239
Isotype IgG1 kappa
Applications WB; ELISA
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-240
Isotype IgG1
Applications WB; IP; ELISA
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-241
Isotype IgG2a Kappa
Applications IP; IF
Host Animal Mouse
Specie Reactivity Rat
Antibody Clone TJL-242
Isotype IgG2b
Applications WB; IP; ELISA
Clear All
Specie Reactivity Human
Type Recombinant Protein
Expression Host HEK293T Cells
Specie Reactivity Rat
Type Recombinant Protein
Expression Host Insect Cells
Specie Reactivity Human
Type Native Protein
Applications Functional Assays
Specie Reactivity Human
Type Recombinant Protein
Expression Host E.coli
Applications Positive Control; Immunogen; WB
Specie Reactivity Mouse
Type Recombinant Protein
Expression Host E.coli
Applications Positive Control; Immunogen; WB
Specie Reactivity Mouse
Type Recombinant Protein
Expression Host Yeast
Applications WB; ELISA
Specie Reactivity Mouse
Type Recombinant Protein
Expression Host E.coli/Mammalian cell/Baculovirus
Applications WB; ELISA
Specie Reactivity Rat
Type Recombinant Protein
Expression Host E.coli
Applications Positive Control; Immunogen; WB
Specie Reactivity Rabbit
Type Recombinant Protein
Expression Host E.coli
Applications Positive Control; Immunogen; WB
Specie Reactivity Pig
Type Recombinant Protein
Expression Host E.coli
Applications Positive Control; Immunogen; WB
Product List Background

Background

C-reactive protein (CRP) is an acute-phase serum protein. It is a member of the pentraxin family, produced mostly by cells in the liver in response to a variety of inflammatory cytokines. The levels of CRP in the blood are closely associated with the degree of inflammatory responses. CRP levels rise rapidly in response to threats such as trauma, inflammation, and infection and fall rapidly in response to remission. Thus, CRP levels are considered as non-specific markers of inflammation, and measurement of CRP levels has important clinical significance for the diagnosis of some inflammatory diseases such as rheumatoid arthritis, lupus, and vasculitis.

CRP has been indicated a role in the innate immune system through activating complement, binding to Fc receptors, and acting as an opsonin for a variety of pathogens. CRP interacts with Fc receptors, leading to the production of pro-inflammatory cytokines that increase the inflammatory response. CRP binds to microbial polysaccharides or to the ligands exposed on damaged cells, leading to the activation of the classical complement pathway and promoting their uptake by phagocytic cells. Importantly, CRP also recognizes altered self and foreign molecules based on pattern recognition, inducing a proinflammatory signal and activating the adaptive immune system. Recent studies have also shown that CRP serves an important role in the inflammatory process, including phagocytosis, nitric oxide release, and cytokine production.

CRP structure. (By Jawahar Swaminathan and MSD staff at the European Bioinformatics Institute - https://www.ebi.ac.uk/pdbe/static/entry/1b09_deposited_chain_front_image-800x800.png, displayed on https://www.ebi.ac.uk/pdbe/entry/pdb/1b09, Public Domain, https://commons.wikimedia.org/w/index.php?curid=6003861)Fig. 1 Structure of CRP.1

Reference

  1. By Jawahar Swaminathan and MSD staff at the European Bioinformatics Institute - https://www.ebi.ac.uk/pdbe/static/entry/1b09_deposited_chain_front_image-800x800.png, displayed on https://www.ebi.ac.uk/pdbe/entry/pdb/1b09, Public Domain, https://commons.wikimedia.org/w/index.php?curid=6003861
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For Research Use Only.