shRNA Adenovirus Serotype 5 (ΔE1/E3), p7SK-(Lsm14a-shRNA-Seq4)(CAT#: AdV-SI3481WQ)

This product is a Lsm14a-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The Lsm14a gene encodes Sm-like proteins that are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. The expression of Lsm14a-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype AdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Modification ΔE1/E3
Insert Lsm14a-shRNA-Seq4
Related Target/Protein Lsm14a
Region 3UTR
TargetSeq CCAGCTAAATGGAACTGCTAA
NCBI RefSeq NM_025948
Alternative Names RAP55; FAM61A; RAP55A; C19orf13
Titer >1*10^10 GC/mL
Target Gene
Gene ID 26065
Uniprot ID Q8ND56

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