Point Mutation Service

A single nucleotide alteration in the DNA sequence is known as a point mutation, and it can have a major effect on how genes operate and how diseases develop. These specific mutations are essential resources for researching genetic processes and creating focused treatments. Creative Biolabs provides reliable CRISPR-based point mutation cell line services, delivering accurate, stable edits to support your research with high efficiency and minimal off-target effects.

Introduction of Point Mutation Service

One nucleotide alteration in the DNA sequence is referred to as a point mutation. These mutations can be silent, missense, or nonsense, and they may modify the function of proteins or interfere with the control of genes. Despite their subtle nature, point mutations are responsible for over 60% of known disease-related genetic variants, playing a central role in cancers, inherited disorders, and neurological diseases. In biomedical research, precise modeling of point mutations is vital for unraveling gene function, understanding disease mechanisms, and advancing targeted therapy development.

Workflow of Point Mutation Service

Fig. 1 Workflow of our gene point mutation service.

Advantages of Point Mutation Service

• High Precision & Specificity - Accurate single-base editing with minimal off-target effects using optimized CRISPR strategies.
• Stable & Reproducible Results - Genomic edits are stably inherited and consistent across cell passages.
• Ideal for Disease Modeling - Precisely replicates pathogenic mutations for in-depth disease mechanism studies.
• Affordable with Excellent Support - Competitive pricing, responsive service, and expert technical assistance throughout the project.
• Flexible & Scalable - Compatible with various cell types and easily tailored to different research needs.

How Point Mutation Service Can Assist Your Project

At Creative Biolabs, we provide high-quality single-cell clones carrying precisely engineered point mutations. Each clone is thoroughly validated, with Sanger sequencing confirming the precise mutation and mycoplasma testing ensuring pure and contamination-free culture. With guaranteed genetic accuracy and a sterile background, our cell lines help researchers avoid common pitfalls and focus on meaningful results—whether for disease modeling, functional studies, or drug discovery.

Reliable mutation models from Creative Biolabs provide a solid foundation for impactful discoveries. Ready to accelerate your research with precision-engineered cell lines? Get in touch with us to talk about your project and get professional assistance catered to your research objectives.