shRNA Adenovirus Serotype 5 (ΔE1/E3), pH1-(LOC392563-shRNA-Seq2)(CAT#: AdV-SI2415WQ)
This product is a LOC392563-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The protein encoded by LOC392563 gene is a component of the mature neuronal cytoskeleton, and it interacts with the zygosome, which is mediated by neurofilament-related proteins. The expression of LOC392563-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | AdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Modification | ΔE1/E3 |
Insert | LOC392563-shRNA-Seq2 |
Related Target/Protein | LOC392563 |
Region | CDS |
TargetSeq | CGCAGAACCATTACAGCGATA |
NCBI RefSeq | XM_373382 |
Titer | >1*10^10 GC/mL |
Related Diseases | Neurodegenerative diseases |