shRNA Adenovirus Serotype 5 (ΔE1/E3), pH1-(Pramel1-shRNA-Seq1)(CAT#: AdV-SI3149WQ)
This product is a Pramel1-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The Pramel1 gene may play a role in acrosome development and also in sperm maturation and motility. The expression of Pramel1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Adenoviridae |
| Species | Adenovirus |
| Serotype | AdV-5 |
| Backbone | AdV-5 (ΔE1/E3) |
| Tropism | Both nondividing and dividing cells |
| Modification | ΔE1/E3 |
| Insert | Pramel1-shRNA-Seq1 |
| Related Target/Protein | Pramel1 |
| Region | CDS |
| TargetSeq | CTACAGGAGAATCTTAGAGAT |
| NCBI RefSeq | NM_031377 |
| Titer | >1*10^10 GC/mL |
| Related Diseases | Infertility |
