shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(WDR25-shRNA-Seq2)(CAT#: AdV-SI0364WQ)
This product is a WDR25-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The WD domains of WDR25 gene are involved in protein-protein interactions in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The expression of WDR25-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | HAdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Insert | WDR25-shRNA-Seq2 |
Related Target/Protein | WDR25 |
Region | 3UTR |
TargetSeq | CTCAAGGGTAGATGAGAGGAA |
NCBI RefSeq | NM_024515 |
Alternative Names | C14orf67 |
Titer | >1*10^10 GC/mL |