Recombinant adenovirus, pU6-(Mouse JP12(Stk11 52-1311bp)), Overexpression(CAT#: AdV-GTOH0060WQ)
The product is an adenovirus vector containing the insertion of JP12(Stk11 52-1311bp) gene. This gene encodes a member of the serine/threonine kinase family. The encoded protein, a known tumor suppressor, activates (via phosphorylation) adenine monophosphate-activated protein kinase (AMPK) and AMPK-related kinase proteins. The product is suitable for stable overexpression of exogenous gene in various types of cells and can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Adenoviridae |
| Species | Adenovirus |
| Tropism | Both nondividing and dividing cells |
| Insert | JP12(Stk11 52-1311bp) |
| Related Target/Protein | Mouse Stk11 |
| NCBI RefSeq | NM_011492 |
| Alternative Names | Lkb1, Par-4, R75140, AA408040 |
| Titer | >1.00E+10 PFU/mL |
| Related Diseases | Peutz-Jeghers syndrome |
| Application | Overexpression |
