siRNA, Anti-CYP2A7, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06053WQ-2OMe)

The product SIRGT06053WQ-2OMe is a type of small interfering RNA (siRNA) that targets CYP2A7 gene and regulates the expression of gene. The siRNA interferes with the expression of CYP2A7 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000764.2; NM_030589.2
Alternative Names CPA7; CPAD; CYP2A; CYPIIA7; P450-IIA4
Related Diseases Metabolism
Purification HPLC
Target Gene
Gene ID 1549
Uniprot ID P20853
Sub Cat Target Species Modification Scale  
SIRGT07053WQ-2F CYP2A7 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08053WQ-2MOE CYP2A7 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09053WQ-LNA CYP2A7 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06053WQ-RB CYP2A7 Human Ribo-modified Inquiry
SIRGT07053WQ-BB CYP2A7 Human Backbone-modified Inquiry

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