siRNA, Anti-CYP3A7, 2'-F/2'-OMe/2'-MOE/LNA/Backbone-modified(CAT#: SIRGT06054WQ-2OMe)

The product SIRGT06054WQ-2OMe is a type of small interfering RNA (siRNA) that targets CYP3A7 gene and regulates the expression of gene. The siRNA interferes with the expression of CYP3A7 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000765.4
Alternative Names CP37; CYPIIIA7; P-450(HFL33); P-450111A7; P450-HFLA
Related Diseases Neonatal Abstinence Syndrome
Purification HPLC
Target Gene
Gene ID 1551
Uniprot ID P24462
Sub Cat Target Species Modification Scale  
SIRGT07054WQ-2F CYP3A7 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08054WQ-2MOE CYP3A7 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09054WQ-LNA CYP3A7 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT07054WQ-BB CYP3A7 Human Backbone-modified Inquiry

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