siRNA, Anti-CYP8B1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06070WQ-2OMe)

The product SIRGT06070WQ-2OMe is a type of small interfering RNA (siRNA) that targets CYP8B1 gene and regulates the expression of gene. The siRNA interferes with the expression of CYP8B1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_004391.2
Alternative Names CP8B; CYP12
Related Diseases Extrahepatic Cholestasis
Purification HPLC
Target Gene
Gene ID 1582
Uniprot ID Q9UNU6
Sub Cat Target Species Modification Scale  
SIRGT07070WQ-2F CYP8B1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08070WQ-2MOE CYP8B1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09070WQ-LNA CYP8B1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06070WQ-RB CYP8B1 Human Ribo-modified Inquiry
SIRGT07070WQ-BB CYP8B1 Human Backbone-modified Inquiry

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