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Magic™ Antibody Discovery - Human Glutaredoxin 1 / GLRX1 (1-106) Membrane Protein, Partial, His- tag (CAT#: MP0187F)

Datasheet
This membrane protein is Human Glutaredoxin 1 / GLRX1 (1-106). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Glutaredoxin 1 / GLRX1
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 12.7 kDa. The protein migrates as 12 kDa under reducing (R) condition (SDS-PAGE).
  • Sequence
  • AA Met 1 - Gln 106 (Accession # NP_001112362).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • E.coli
  • Tag
  • His tag at the N-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with 1 mM DTT. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Glutaredoxin 1 / GLRX1
  • Full Name
  • glutaredoxin
  • Introduction
  • This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
  • Alternative Names
  • GRX; GRX1; glutaredoxin-1; TTase-1; thioltransferase; thioltransferase-1

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