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Magic™ Antibody Discovery - Mouse VEGFR2 / KDR (20-762) Membrane Protein, Partial, -mIgG2a Fc tag, low endotoxin (CAT#: MP0516F)

Datasheet
This membrane protein is Mouse VEGFR2 / KDR (20-762). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Mouse
  • Target Protein
  • VEGFR2 / KDR
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 110.1 kDa. The protein migrates as 120-135 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Ala 20 - Glu 762 (Accession # P35918-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • HEK293
  • Tag
  • Mouse IgG2a Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • VEGFR2 / KDR
  • Full Name
  • kinase insert domain protein receptor
  • Introduction
  • Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
  • Alternative Names
  • Flk; orv; Flk-; Flk1; Ly73; VEGF; Flk-1; Krd-1; VEGFR; VEGFR2; VEGFR-2; sVEGFR-2; 6130401C07; vascular endothelial growth factor receptor 2; VEGF receptor-2; fetal liver kinase 1; kinase NYK; protein-tyrosine kinase receptor flk-1; soluble vascular endothelial growth factor receptor 2; vascular endothelial growth factor receptor-3

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