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Magic™ Membrane Protein Human ABCA5 (ATP binding cassette subfamily A member 5) Full Length (CAT#: MPC2248K) Made to Order

Datasheet
This product is a 186.5 kDa Human ABCA5 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ABCA5
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 186.5 kDa
  • TMD
  • 15
  • Sequence
  • MSTAIREVGVWRQTRTLLLKNYLIKCRTKKSSVQEILFPLFFLFWLILIS
    MMHPNKKYEEVPNIELNPMDKFTLSNLILGYTPVTNITSSIMQKVSTDHL
    PDVIITEEYTNEKEMLTSSLSKPSNFVGVVFKDSMSYELRFFPDMIPVSS
    IYMDSRAGCSKSCEAAQYWSSGFTVLQASIDAAIIQLKTNVSLWKELEST
    KAVIMGETAVVEIDTFPRGVILIYLVIAFSPFGYFLAIHIVAEKEKKIKE
    FLKIMGLHDTAFWLSWVLLYTSLIFLMSLLMAVIATASLLFPQSSSIVIF
    LLFFLYGLSSVFFALMLTPLFKKSKHVGIVEFFVTVAFGFIGLMIILIES
    FPKSLVWLFSPFCHCTFVIGIAQVMHLEDFNEGASFSNLTAGPYPLIITI
    IMLTLNSIFYVLLAVYLDQVIPGEFGLRRSSLYFLKPSYWSKSKRNYEEL
    SEGNVNGNISFSEIIEPVSSEFVGKEAIRISGIQKTYRKKGENVEALRNL
    SFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDE
    MFEARKMIGICPQLDIHFDVLTVEENLSILASIKGIPANNIIQEVQKVLL
    DLDMQTIKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSR
    HIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGSSMFL
    KSKWGIGYRLSMYIDKYCATESLSSLVKQHIPGATLLQQNDQQLVYSLPF
    KDMDKFSGLFSALDSHSNLGVISYGVSMTTLEDVFLKLEVEAEIDQADYS
    VFTQQPLEEEMDSKSFDEMEQSLLILSETKAALVSTMSLWKQQMYTIAKF
    HFFTLKRESKSVRSVLLLLLIFFTVQIFMFLVHHSFKNAVVPIKLVPDLY
    FLKPGDKPHKYKTSLLLQNSADSDISDLISFFTSQNIMVTMINDSDYVSV
    APHSAALNVMHSEKDYVFAAVFNSTMVYSLPILVNIISNYYLYHLNVTET
    IQIWSTPFFQEITDIVFKIELYFQAALLGIIVTAMPPYFAMENAENHKIK
    AYTQLKLSGLLPSAYWIGQAVVDIPLFFIILILMLGSLLAFHYGLYFYTV
    KFLAVVFCLIGYVPSVILFTYIASFTFKKILNTKEFWSFIYSVAALACIA
    ITEITFFMGYTIATILHYAFCIIIPIYPLLGCLISFIKISWKNVRKNVDT
    YNPWDRLSVAVISPYLQCVLWIFLLQYYEKKYGGRSIRKDPFFRNLSTKS
    KNRKLPEPPDNEDEDEDVKAERLKVKELMGCQCCEEKPSIMVSNLHKEYD
    DKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDI
    EPTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLWPDTTLQEHFEIYGA
    VKGMSASDMKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGN
    PQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVC
    DRVAIMVSGQLRCIGTVQHLKSKFGKGYFLEIKLKDWIENLEVDRLQREI
    QYIFPNASRQESFSSILAYKIPKEDVQSLSQSFFKLEEAKHAFAIEEYSF
    SQATLEQVFVELTKEQEEEDNSCGTLNSTLWWERTQEDRVVF

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • StrepII and Flag tag at the N-terminus
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ABCA5
  • Full Name
  • ATP binding cassette subfamily A member 5
  • Introduction
  • The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.
  • Alternative Names
  • ABCA5; HTC3; ABC13; EST90625; cholesterol transporter ABCA5; ATP-binding cassette A5; ATP-binding cassette, sub-family A (ABC1), member 5; ATP binding cassette subfamily A member 5

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