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Magic™ Membrane Protein Human ADRA2C (Adrenoceptor alpha 2C) Full Length (CAT#: MPC0030K) Made to Order

Datasheet
This product is a 49.5 kDa Human ADRA2C membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ADRA2C
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 49.5 kDa
  • TMD
  • 7
  • Sequence
  • MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGA
    VAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILV
    ATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRY
    WSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYP
    QCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAP
    VGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGA
    LRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASS
    RSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFF
    SYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKH
    ILFRRRRRGFRQ

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ADRA2C
  • Full Name
  • Adrenoceptor alpha 2C
  • Introduction
  • Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.
  • Alternative Names
  • ADRA2L2; ADRARL2; ADRA2RL2; ALPHA2CAR; adrenergic, alpha-2C-, receptor; alpha-2 adrenergic receptor subtype C4; alpha-2C adrenoceptor; alpha-2C adrenoreceptor; alpha-2CAR; alpha2-AR-C4; ADRA2C; Adrenoceptor alpha 2C

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