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Magic™ Membrane Protein Human GPR153 (G protein-coupled receptor 153) Full Length (CAT#: MPC0131K) Made to Order

Datasheet
This product is a 65.3 kDa Human GPR153 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GPR153
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 65.3 kDa
  • TMD
  • 7
  • Sequence
  • MSDERRLPGSAVGWLVCGGLSLLANAWGILSVGAKQKKWKPLEFLLCTLA
    ATHMLNVAVPIATYSVVQLRRQRPDFEWNEGLCKVFVSTFYTLTLATCFS
    VTSLSYHRMWMVCWPVNYRLSNAKKQAVHTVMGIWMVSFILSALPAVGWH
    DTSERFYTHGCRFIVAEIGLGFGVCFLLLVGGSVAMGVICTAIALFQTLA
    VQVGRQADRRAFTVPTIVVEDAQGKRRSSIDGSEPAKTSLQTTGLVTTIV
    FIYDCLMGFPVLVVSFSSLRADASAPWMALCVLWCSVAQALLLPVFLWAC
    DRYRADLKAVREKCMALMANDEESDDETSLEGGISPDLVLERSLDYGYGG
    DFVALDRMAKYEISALEGGLPQLYPLRPLQEDKMQYLQVPPTRRFSHDDA
    DVWAAVPLPAFLPRWGSGEDLAALAHLVLPAGPERRRASLLAFAEDAPPS
    RARRRSAESLLSLRPSALDSGPRGARDSPPGSPRRRPGPGPRSASASLLP
    DAFALTAFECEPQALRRPPGPFPAAPAAPDGADPGEAPTPPSSAQRSPGP
    RPSAHSHAGSLRPGLSASWGEPGGLRAAGGGGSTSSFLSSPSESSGYATL
    HSDSLGSAS

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • GPR153
  • Full Name
  • G protein-coupled receptor 153
  • Introduction
  • This gene encodes an integral membrane protein that belongs to the Class A rhodopsin superfamily of G protein coupled receptors. The encoded protein is expressed primarily in the central nervous system. A knockdown of the orthologous gene in rat is associated with a significant reduction in food intake and impaired decision making ability. Mutations in this gene are associated with schizophrenia, autism, and other neuropsychiatric disorders. The expression of this gene is activated by the glioma-associated oncogene homolog 1 transcription factor which, in turn, is activated by sonic hedgehog in normal and tumorigenic cells.
  • Alternative Names
  • PGR1; probable G-protein coupled receptor 153; G-protein coupled receptor PGR1; GPR153; G protein-coupled receptor 153

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