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Magic™ Membrane Protein Human FKRP (Fukutin related protein) Full Length (CAT#: MPC2272K) Made to Order

This product is a 54.5 kDa Human FKRP membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • FKRP
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • Molecular Weight
  • 54.5 kDa
  • TMD
  • 1
  • Sequence
  • MRLTRCQAALAAAITLNLLVLFYVSWLQHQPRNSRARGPRRASAAGPRVT
    VLVREFEAFDNAVPELVDSFLQQDPAQPVVVAADTLPYPPLALPRIPNVR
    LALLQPALDRPAAASRPETYVATEFVALVPDGARAEAPGLLERMVEALRA
    GSARLVAAPVATANPARCLALNVSLREWTARYGAAPAAPRCDALDGDAVV
    LLRARDLFNLSAPLARPVGTSLFLQTALRGWAVQLLDLTFAAARQPPLAT
    AHARWKAEREGRARRAALLRALGIRLVSWEGGRLEWFGCNKETTRCFGTV
    VGDTPAYLYEERWTPPCCLRALRETARYVVGVLEAAGVRYWLEGGSLLGA
    ARHGDIIPWDYDVDLGIYLEDVGNCEQLRGAEAGSVVDERGFVWEKAVEG
    DFFRVQYSESNHLHVDLWPFYPRNGVMTKDTWLDHRQDVEFPEHFLQPLV
    PLPFAGFVAQAPNNYRRFLELKFGPGVIENPQYPNPALLSLTGSG

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • StrepII and Flag tag at the N-terminus
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • FKRP
  • Full Name
  • Fukutin related protein
  • Introduction
  • This gene encodes a protein which is targeted to the medial Golgi apparatus and is necessary for posttranslational modification of dystroglycan. Mutations in this gene have been associated with congenital muscular dystrophy, cognitive disability, and cerebellar cysts. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
  • Alternative Names
  • FKRP; FKTR; MDC1C; LGMD2I; LGMDR9; MDDGA5; MDDGB5; MDDGC5; fukutin-related protein; ribitol-5-phosphate transferase; Fukutin related protein

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