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Magic™ Membrane Protein Human IFNAR1 (Interferon alpha and beta receptor subunit 1) Expressed in NS0 for Antibody Discovery, Partial (26-436aa) (CAT#: MPX0581K)

Datasheet
This product is a 47.2 kDa Human IFNAR1 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IFNAR1
  • Protein Length
  • Partial (26-436aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 47.2 kDa
  • TMD
  • 1
  • Sequence
  • AGGKNLKSPQKVEVDIIDDNFILRWN
    RSDESVGNVTFSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEI
    KLRIRAEKENTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAIVIHISPGT
    KDSVMWALDGLSFTYSLVIWKNSSGVEERIENIYSRHKIYKLSPETTYCL
    KVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWDY
    TYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQK
    GIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYI
    GAPKQSGNTPVIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLT
    VYCVKARAHTMDEKLNKSSVFSDAVCEKTKPGNTSK

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • IFNAR1
  • Full Name
  • Interferon alpha and beta receptor subunit 1
  • Introduction
  • The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor.
  • Alternative Names
  • IFNAR1; AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC; interferon alpha/beta receptor 1; CRF2-1; IFN-R-1; IFN-alpha/beta receptor 1; IFNalpha/beta receptor 1; alpha-type antiviral protein; beta-type antiviral protein; cytokine receptor class-II member 1; cytokine receptor family 2 member 1; interferon (alpha, beta and omega) receptor 1; interferon receptor 1; interferon-alpha/beta receptor alpha chain; interferon-beta receptor 1; type I interferon receptor 1; Interferon alpha and beta receptor subunit 1

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