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Magic™ Membrane Protein Human STX1A (Syntaxin 1A) expressed in E. coli for Antibody Discovery (CAT#: MP0008Q)

Datasheet
This product is a 26.1 kDa Human STX1A membrane protein expressed in E. col. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • STX1A
  • Protein Length
  • Partial
  • Protein Class
  • Druggable Genome, Secreted Protein, Transmembrane
  • Molecular Weight
  • 26.1 kDa
  • TMD
  • 1
  • Sequence
  • MKDRTQELRTAKDSDDDDDVAVTVDRDRFM DEFFEQVEEI RGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSI EQEEGLNRSS ADLRIRKTQH STLSRKFVEV MSEYNATQSDYRERCKGRIQ RQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHS EIIKLENSIRELHDMFMDMA MLVESQ

Product Description

  • Expression Systems
  • E. coli
  • Tag
  • CaM
  • Purification
  • Conventional chromatography
  • Purity
  • ≥95 by SDS PAGE
  • Buffer
  • 20 mM Tris (pH 7.5), 1 mM DTT, 10% glycerol

Target

  • Target Protein
  • STX1A
  • Full Name
  • Syntaxin 1A
  • Introduction
  • This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • STX1; HPC-1; P35-1; SYN1A; syntaxin-1A; neuron-specific antigen HPC-1; syntaxin 1A (brain)

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