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Magic™ Membrane Protein Human PTPRD (Protein tyrosine phosphatase receptor type D) Expressed in HEK293 for Antibody Discovery, Partial (21-1174aa) (CAT#: MPX0226K)

Datasheet
This product is a 154 kDa Human PTPRD membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PTPRD
  • Protein Length
  • Partial (21-1174aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 154 kDa
  • TMD
  • 1
  • Sequence
  • ETPPRFTRTPVDQTGVSGGVASFICQATGD
    PRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVA
    SNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAAS
    GNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEES
    DQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPG
    GSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANY
    TCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEP
    VSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIG
    RGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQG
    YRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGD
    GPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELV
    YKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEI
    SARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYT
    AVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESL
    SVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVH
    YVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTV
    TAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTALIQWHPPVDTF
    GPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNK
    VGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGI
    ITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSK
    GPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMPF
    KILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVT
    AKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANENIKGYYIIIVPLKKS
    RGKFIKPWESPDEMELDELLKEIS

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 400 μg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >80%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.

Target

  • Target Protein
  • PTPRD
  • Full Name
  • Protein tyrosine phosphatase receptor type D
  • Introduction
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5.
  • Alternative Names
  • PTPRD; HPTP; PTPD; HPTPD; HPTPDELTA; RPTPDELTA; R-PTP-delta; receptor-type tyrosine-protein phosphatase delta; protein tyrosine phosphatase, receptor type, delta polypeptide; rceptor-type tyrosine-protein phosphatase delta; Protein tyrosine phosphatase receptor type D

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