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NativeExtract™ Human C5AR2 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX420)

Datasheet
This product is recombinant Human C5AR2 protein in native nanodisc form. The synthetic compound we developed can solubilize the C5AR2 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • C5AR2
  • Protein Length
  • Full length
  • Molecular Weight
  • 36.1 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • C5AR2
  • Full Name
  • Complement C5a receptor 2
  • Introduction
  • This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • C5L2; GPF77; GPR77; C5a anaphylatoxin chemotactic receptor 2; C5a anaphylatoxin chemotactic receptor C5L2; G protein-coupled receptor 77; G protein-coupled receptor C5L2; C5AR2; Complement C5a receptor 2

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