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NativeExtract™ Human CX3CR1 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX380)

Datasheet
This product is recombinant Human CX3CR1 protein in native nanodisc form. The synthetic compound we developed can solubilize the CX3CR1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CX3CR1
  • Protein Length
  • Full length
  • Molecular Weight
  • 40.4 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CX3CR1
  • Full Name
  • C-X3-C motif chemokine receptor 1
  • Introduction
  • C-X3-C motif chemokine receptor 1Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.
  • Alternative Names
  • V28; CCRL1; GPR13; CMKDR1; GPRV28; CMKBRL1; CX3C chemokine receptor 1; C-X3-C CKR-1; CMK-BRL-1; CMK-BRL1; G-protein coupled receptor 13; beta chemokine receptor-like 1; chemokine (C-C) receptor-like 1; chemokine (C-X3-C motif) receptor 1; chemokine (C-X3-C) receptor 1; fractalkine receptor; CX3CR1; C-X3-C motif chemokine receptor 1

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