As an industry leading expert in antibody production and engineering, Creative Biolabs is committed to offering high-quality premade antibody library screening services against numerous targets. Based on our plentiful premade library resources and vast experience, we are confident in tailoring our customers the most efficient and reliable service to accelerate their cutting-edge projects. Our professional scientists are happy to help global researchers screen specific anti-idiotype antibody from our premade phage displayed antibody library.
Anti-idiotype antibodies (anti-Id Abs) are antibodies binding to idiotopes that are located in the variable region, including the antigen binding site, of another antibody. Since anti-ID Abs are capable of binding to antibody drugs within biological fluids, they are widely used as diagnostic reagents for the detection, identification, and analysis of therapeutic drugs to support pre-clinical and downstream clinical trials. Similarly, it can be used as a positive control for human anti-human antibody (HAHA), human anti-chimeric antibody (HACA) or human anti-murine antibody (HAMA) immune responses to the administered antibody. Furthermore, anti-Id vaccines against different antigens, including tumor-associated antigens, have been developed for the treatment of multiple diseases.
Traditionally, anti-idiotypes are developed by immunization of animals with antibodies particular for a given antigen. However, the process could be laborious and time-consuming, especially employing traditional hybridoma technology. By taking advantage of phage display technology, anti-Id single chain Fv (scFv) antibody could be rapidly identified through rounds of panning against idiotype antibody antigen based on epitope antibody discovery strategies. As a leading service provider in the field of phage display, Creative Biolabs has established many naïve as well as well-designed synthetic phage displayed antibody libraries for the discovery of impeccable binder with affinity ranging from pM to nM. Our experienced scientists are happy to help global researchers screen high affinity anti-Id antibodies which are specific to the downstream applications. Our premade phage displayed antibody libraries include:
Libraries | Library ID | Display Technology | Library Format | Species | Library Size |
Phage display human scFv libraries | HuScL-2 | Phage Display | scFv | Human | 1.42×109 |
HuScL-4 | Phage Display | scFv | Human | 2.0×109 | |
HuScL-6 | Phage Display | scFv | Human | 1.0×1011 | |
HuScL-7 | Phage Display | scFv | Human | 1.1×1010 | |
Phage display human Fab libraries | HuFabL-4 | Phage Display | Fab | Human | 1.9×1010 |
HuFabL-5 | Phage Display | Fab | Human | 1.1×1010 | |
HuFabssL-1 | Phage Display | Fab | Human | 1.8×1010 |
Creative Biolabs also provides antibody discovery services for different types of targets to suit a variety of applications:
Creative Biolabs has more than ten years' experience in developing of highly sensitive and specific anti-Id antibodies for antibody drug development. Our scientists will work as closely as possible with you to understand your specific requirement in order to generate perfect anti-Id antibodies. Besides anti-Id antibody, we also offer premade phage displayed antibody library screening services for TCR-like and anti-PTM antibody discovery. Learn more about our premade antibody library screening service, please feel free to contact us.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.