Premade Antibody Library based Anti-PTM Antibody Discovery Service

As an excellent service provider in premade antibody library screening, Creative Biolabs offers high quality antibody discovery service for global customers. According to customer's detailed requirements, we are able to screen numerous specific antibodies against the custom targets, using our plentiful premade library resources. With our vast experience and well-established platform, we are confident in screening specific anti-PTM antibody for global multiple applications.

Anti-PTM Antibody

Post-translational modifications (PTMs) of proteins, including methylation, acetylation, phosphorylation, glycosylation and ubiquitination, play key roles in many biological processes, such as cell signaling, gene transcription regulation, protein degradation and cell-cell adhesion. Also, PTMs is associated with diseases such as cancer. Thus, identification and quantification of PTMs are critical for a fundamental understanding of cell biology and for elucidating disease mechanisms. During the past, anti-PTM antibodies have been used as the specific reagents to analyze the existence or relative amounts of the modified protein or to more quantitatively characterize cell populations bearing the modification of interest.

Premade Phage Displayed Antibody Library Screening for Anti-PTM Antibody Discovery

Generally, anti-PTM antibodies are produced by animal immunization methods. However, affinity and specificity among different antibody products to the same PTM vary significantly. In addition, most of current antibodies to PTMs are polyclonal antibodies that cannot be reproduced, which bringing a serious impediment in obtaining reproducible and reliable data. With years of experience in antibody production, Creative Biolabs has established advanced phage display platforms, which enables us to identify specific anti-PTM antibodies from our large naïve, immunized and synthetic libraries with affinity ranging from pM to nM. According to your novel requirement, our experienced scientists will tailor biopanning strategy to increase of candidates with higher affinity and desired specificity. Premade phage displayed antibody libraries in Creative Biolabs include:

Libraries	Library ID	Display Technology	Library Format	Species	Library Size
Phage display human scFv libraries	HuScL-2	Phage Display	scFv	Human	1.42×10⁹
	HuScL-4	Phage Display	scFv	Human	2.0×10⁹
	HuScL-6	Phage Display	scFv	Human	1.0×10¹¹
	HuScL-7	Phage Display	scFv	Human	1.1×10¹⁰
Phage display human Fab libraries	HuFabL-4	Phage Display	Fab	Human	1.9×10¹⁰
	HuFabL-5	Phage Display	Fab	Human	1.1×10¹⁰
	HuFabssL-1	Phage Display	Fab	Human	1.8×10¹⁰

Creative Biolabs also provides antibody discovery services for different types of targets to suit a variety of applications:

Advantages of Our Service

Numerous targets can be screened, including purifies targets, unpurified targets, intact cells, tissues, or any in vivo targets
Plentiful library resources with large capacity and diversity
One-stop services from antibody discovery to downstream PK/PD and immunogenicity evaluation
Optimal study design and data interpretation with fast turnaround time

In terms of years of experience in phage display realm, Creative Biolabs has served our global clients with high-quality library screening services. Our scientists are confident in tailoring the most reliable and cost-effective protocol to facilitate worldwide researchers' programs. Except for anti-PTM antibody, we also offer premade phage displayed antibody library screening services for TCR-like and anti-Id antibody discovery. Learn more about our premade antibody library screening service, please feel free to contact us.

All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.

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