Creative Biolabs provides world-class premade antibody library screening services based on the latest phage display technology platform. Our scientists have integrated a comprehensive portfolio of premade phage display libraries to promote the development of global researchers' programs, including but not limited to antibody discovery for immunotherapy.
Immunotherapy is a type of cancer treatment that boosts the body's natural defenses to fight cancer. It involves the use of therapeutic modalities that lead to a manipulation of the immune system by using immune agents such as cytokines, vaccines, cell therapies, and transfection agents. Currently, numerous antibody-based immunotherapy approaches have been developed to enhance the innate powers of the immune system to fight cancer, including CAR-T cells therapy (premade phage displayed antibody library screening for CAR-T therapy), immune checkpoint inhibitor (premade phage displayed antibody library screening for immune checkpoint therapy), and ADC therapy (premade phage displayed antibody library screening for ADC therapy). CAR-T therapy consists of removing immune cells from a patient and genetically modifying them to enhance their immune activity, and then re-introduce them into the patient. Immune checkpoint inhibitors work by targeting molecules that serve as checks in the regulation of immune responses and block inhibitory molecules or activate stimulatory molecules. ADC, which is comprised of a monoclonal antibody tethered to a cytotoxic drug (known as the payload) via a chemical linker, is designed to selectively deliver the ultratoxic payload directly to the target cancer cells.
In the past, phage display has become one of the most effective ways for producing large amounts of specific peptides, proteins, and antibodies in a relatively short time. Recently, phage display libraries have been used to isolate human monoclonal antibodies directed toward various antigens, including markers of tumor. As a pioneer company in the field of antibody discovery, Creative Biolabs has constructed multiple high-quality libraries. Our professional scientists are happy to tailor the most appropriate biopanning strategies to select high-affinity binders or ligands to recognize the novel targets. The premade phage displayed antibody libraries available at Creative Biolabs include:
Libraries | Library ID | Display Technology | Library Format | Species | Library Size |
Phage display human scFv libraries | HuScL-2 | Phage Display | scFv | Human | 1.42×109 |
HuScL-4 | Phage Display | scFv | Human | 2.0×109 | |
HuScL-6 | Phage Display | scFv | Human | 1.0×1011 | |
HuScL-7 | Phage Display | scFv | Human | 1.1×1010 | |
HuScL-2S | Phage Display | scFv | Human | 2.36×1010 | |
Phage display human Fab libraries | HuFabL-4 | Phage Display | Fab | Human | 1.9×1010 |
HuFabL-5 | Phage Display | Fab | Human | 1.1×1010 | |
HuFabssL-1 | Phage Display | Fab | Human | 1.8×1010 |
Creative Biolabs also provides antibody discovery services for different types of targets to suit a variety of applications:
Creative Biolabs is dedicated to developing and optimizing the effectiveness and the efficiency of phage display library screening.
With years of experience, our scientists have developed several biopanning methods to boost our global customers' research and project goals. For more detailed information about how we can aid your project, please feel free to contact us.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
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Email: info@creative-biolabs.com |