AF488-labeled Human BCMA CAR Detection Reagent, His Tag (XS-1223-LX1)

Online Inquiry Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Specific Inquiry

Add to Cart

Specifications

Target
BCMA

Organism
Human

Application
Used for evaluating CAR expression.

Purity
>90%

Endotoxin Level
Less than 1.0 EU per μg by the LAL method.

Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please protect from light and avoid repeated freeze-thaw cycles.

Shelf-Life
Stable as supplied until expiry date on label.

Application Notes
This product is recommended for FC application, and the optimal working dilutions should be determined by the end user.

Diseases
Multiple myeloma, leukemia, B-Cell lymphoma

Molecular Characterization
It contains AA Met 1 - Ala 54 (Accession # Q02223-1). It is the AF488 labeled form of Human BCMA, His Tag.

Conjugation
AF488

Size
25µg; 100µg

Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Expression
Human HEK293 cells

Host Species
Human

Species Reactivity
Human

Form
Lyophilized

Target

Target Introduction
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.

Target Alternative Names
TNF receptor superfamily member 17

Entrez Gene ID
100133941

UniProt ID
Q02223-1

Related Resources

Overview of BCMA-Targeted CAR Cell Therapies

Customer Reviews and Q&As

There are currently no customer reviews or questions for AF488-labeled Human BCMA CAR Detection Reagent, His Tag (XS-1223-LX1). Click the button below to contact us or submit your feedback about this product.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.