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Anti-TEAD1 T cell receptor (K1), pCDTCR1 (TCR-YC1177)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The vector of anti-TEAD1 T cell receptor (TCR) is constructed for the engineering of T cell to target TEAD1 protein (VLENFTILLV) restricted by HLA-A2. The T cells are genetically modified through transduction with a lentiviral vector expressing TEAD1-specific T cell receptor.

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Details

  • Target
  • TEAD1
  • Target Species
  • Human
  • Epitope
  • VLENFTILLV
  • Format
  • Non-Modified TCR
  • Allele
  • HLA-A2
  • Targeting Diseases
  • Sveinsson's chorioretinal atrophy
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~ 8 kb
  • Vector Type
  • Lentiviral vector
  • TCR Clone
  • K1
  • Host Species
  • Human

Target

  • Introduction
  • This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been described but their full-length natures have not been experimentally verified.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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