Armenian hamster Anti-Mouse CD55 Monoclonal Antibody (CTJS-657) [Biotin](Cat#: CTA-685)
This product is a conjugated anti-Mouse Complement Decay-Accelerating Factor (CD55) Monoclonal antibody (CTJS-657) generated from the Armenian hamster. The antibody can be used for ELISA, FC, WB.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-657 |
| Host Animal |
Armenian hamster |
| Isotype |
IgG |
| Immunogen |
GPI-DAF transfected CHO cells |
| Species Reactivity |
Mouse |
| Applications |
ELISA; FC; WB |
| Application Notes |
FC: 0.2 µg/10^6 cells
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Mouse Complement Decay-Accelerating Factor (CD55). |
| Purity |
≥95% as determined by SDS-PAGE |
| Conjugation |
Biotin |
| Format |
Liquid |
| Size |
100 µg |
| Storage |
Store in dark at 4°C. Do Not Freeze. |
| Type |
Primary Antibody |
Target
| Target Name |
CD55 |
| Alternative Names |
CD55 Molecule (Cromer Blood Group); CD55 Molecule, Decay Accelerating Factor For Complement (Cromer Blood Group); Complement Decay-Accelerating Factor; CD55 Antigen; DAF; Decay Accelerating Factor For Complement (CD55, Cromer Blood Group System); Cromer Blood Group Antigen; CD55 |
| Gene ID |
13136 |
| UniProt ID |
Q61475 |
Information
| Introduction |
This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage.
Acts as a receptor for Coxsackievirus A21, coxsackieviruses B1, B3 and B5.
Acts as a receptor for Human enterovirus 70 and D68.
Acts as a receptor for Human echoviruses 6, 7, 11, 12, 20 and 21. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
